Across TCGA patient cohorts, VSTM2B mutation is significantly associated with the total protein of many other genes, with 10 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible VSTM2B-associated genes across cancer lineages are A-Raf_pS299, ERK2, and Ku80. Each is linked with VSTM2B in more than 1 cancer types. Because this analysis shows association rather than direction, both VSTM2B-to-partner and partner-to-VSTM2B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VSTM2B→partner) and Y-score (partner→VSTM2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	A-Raf_pS299 →	-0.166	-3.169	.003	.019	3	1
UCEC	ERK2 →	+0.219	+2.999	.018	.035	3	1
UCEC	Ku80 →	+0.271	+3.179	.017	.010	3	1
UCEC	Di-Ras3 →	-0.216	-3.584	.002	.002	3	1
COAD	INPP4B →	-0.499	-2.991	.009	.036	3	1
COAD	Rab11 →	+0.188	+3.025	.025	.019	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

Exploration

VSTM2B survival (RNA) · tumor vs normal (RNA) · all VSTM2B data types