Across TCGA cell cohorts, VSTM2B mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible VSTM2B-associated genes across cancer lineages are LGALS13, IL9, and LY6G6F. Each is linked with VSTM2B in more than 1 cancer types. Because this analysis shows association rather than direction, both VSTM2B-to-partner and partner-to-VSTM2B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VSTM2B→partner) and Y-score (partner→VSTM2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	LGALS13 →	+0.056	+5.087	<.001	.004	3	1
URINARY_TRACT	IL9 →	+0.130	+5.087	<.001	.004	3	1
URINARY_TRACT	LY6G6F →	+0.040	+5.087	<.001	.004	3	1
BLOOD_Leukemia	GUCA1C →	+0.029	+4.969	<.001	.003	3	1
LARGE_INTESTINE	MSGN1 →	+0.056	+3.345	.007	.007	3	1
LARGE_INTESTINE	C16orf96 →	+0.610	+4.237	.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

Exploration

VSTM2B survival (RNA) · tumor vs normal (RNA) · all VSTM2B data types