VSIR

Across TCGA cell cohorts, VSIR RNA expression is significantly associated with the RNA expression of many other genes, with 10,723 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible VSIR-associated genes across cancer lineages are EHD2, ALDH3B1, and GPRC5A. Each is linked with VSIR in more than 13 cancer types. Because this analysis shows association rather than direction, both VSIR-to-partner and partner-to-VSIR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VSIR versus EHD2 in LUNG_NSCLC_LUSC, with a Pearson correlation of 0.72.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VSIR→partner) and Y-score (partner→VSIR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	EHD2 →	+3.409	+2.776	<.001	<.001	3	14
LUNG_NSCLC_LUSC	ALDH3B1 →	+3.457	+3.458	<.001	<.001	3	12
OESOPHAGUS	GPRC5A →	+4.540	+2.175	<.001	<.001	3	12
OVARY	TBC1D2 →	+2.127	+2.338	<.001	<.001	3	11
BONE	ANXA11 →	+1.050	+2.215	.001	.001	3	11
LUNG_NSCLC_LUSC	RRAS →	+2.311	+2.227	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,723 associations by consensus.

VSIR vs EHD2 — LUNG_NSCLC_LUSC

Explore this scatter interactively →