Across TCGA pan-cancer cohorts, VSIG10L mass-spec protein is linked to patient survival in 1 of 34 cancer types, making it a survival-associated VSIG10L data layer compared with 25 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher VSIG10L mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated VSIG10L expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

HNSC are the cancer types where VSIG10L mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	All	0.966	0.768	<.001	96	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

Exploration

Same gene, other analysis: VSIG10L tumor-vs-normal RNA expression · all VSIG10L data types