Across TCGA patient cohorts, VSIG10L mutation is significantly associated with the total protein of many other genes, with 21 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible VSIG10L-associated genes across cancer lineages are MEK1, ATM, and 14-3-3_beta. Each is linked with VSIG10L in more than 1 cancer types. Because this analysis shows association rather than direction, both VSIG10L-to-partner and partner-to-VSIG10L results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VSIG10L→partner) and Y-score (partner→VSIG10L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MEK1 →	+0.421	+2.906	.004	.001	3	2
UCEC	ATM →	-0.490	-3.156	.007	.018	3	2
UCEC	14-3-3_beta →	-0.099	-2.432	.014	.018	3	1
UCEC	EGFR_pY1068 →	-0.220	-1.906	.029	.016	3	1
UCEC	eIF4E →	+0.227	+3.584	.007	.002	3	1
UCEC	JNK2 →	+0.268	+3.594	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

Exploration

VSIG10L survival (RNA) · tumor vs normal (RNA) · all VSIG10L data types