VRK1

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, VRK1 RNA expression is significantly associated with the protein abundance of many other proteins, with 24,088 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible VRK1-associated proteins across cancer lineages are KPNA2, MCM2, and MCM3. Each is linked with VRK1 in more than 8 cancer types. Because this analysis shows association rather than direction, both VRK1-to-partner and partner-to-VRK1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VRK1 versus KPNA2 in BRCA, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (VRK1→partner) and Y-score (partner→VRK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAKPNA2 →+0.878+0.642<.001<.00139
LUADMCM2 →+0.709+0.700<.001<.00139
LUADMCM3 →+0.770+0.680<.001<.00139
LUADMCM4 →+0.774+0.679<.001<.00139
LUADMCM5 →+0.738+0.679<.001<.00139
LUADMCM6 →+0.745+0.679<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 24,088 associations by consensus.

VRK1 vs KPNA2 — BRCA

Per-sample scatter of VRK1 vs KPNA2 in BRCA (Pearson r = 0.43).

Explore this scatter interactively →

Exploration