VRK1

Across TCGA cell cohorts, VRK1 RNA expression is significantly associated with the RNA expression of many other genes, with 10,760 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible VRK1-associated genes across cancer lineages are DLGAP5, WDHD1, and TDP1. Each is linked with VRK1 in more than 17 cancer types. Because this analysis shows association rather than direction, both VRK1-to-partner and partner-to-VRK1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VRK1 versus DLGAP5 in OESOPHAGUS, with a Pearson correlation of 0.82.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VRK1→partner) and Y-score (partner→VRK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	DLGAP5 →	+2.037	+1.748	<.001	<.001	3	18
OESOPHAGUS	WDHD1 →	+1.767	+1.731	<.001	<.001	3	18
BREAST	TDP1 →	+1.194	+1.043	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	HNRNPC →	+0.801	+1.251	<.001	<.001	3	18
BLOOD_Myeloma	PAPOLA →	+1.138	+1.342	<.001	.003	3	18
OESOPHAGUS	SASS6 →	+1.354	+1.611	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,760 associations by consensus.

VRK1 vs DLGAP5 — OESOPHAGUS

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