VPS54

Across TCGA patient cohorts, VPS54 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,690 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible VPS54-associated proteins across cancer lineages are VSIR, ZNF24, and LGALSL. Each is linked with VPS54 in more than 4 cancer types. Because this analysis shows association rather than direction, both VPS54-to-partner and partner-to-VPS54 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VPS54 versus VSIR in UCEC, with a Pearson correlation of -0.24.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (VPS54→partner) and Y-score (partner→VPS54) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	VSIR →	-0.484	-0.310	<.001	<.001	3	5
LSCC	ZNF24 →	+0.223	+0.374	.006	<.001	3	5
UCEC	LGALSL →	+0.358	+0.339	<.001	.001	3	5
HNSC	HCFC1 →	+0.207	+0.472	.001	.002	3	5
LUAD	SSB →	+0.284	+0.416	<.001	<.001	3	5
LSCC	CDC73 →	+0.289	+0.516	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,690 associations by consensus.

VPS54 vs VSIR — UCEC

Explore this scatter interactively →