VPS54

Across TCGA patient cohorts, VPS54 protein abundance is significantly associated with the RNA expression of many other genes, with 3,271 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible VPS54-associated genes across cancer lineages are SNORA80E, ARHGEF26, and WASF2. Each is linked with VPS54 in more than 2 cancer types. Because this analysis shows association rather than direction, both VPS54-to-partner and partner-to-VPS54 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VPS54 versus SNORA80E in UCEC, with a Pearson correlation of -0.23.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VPS54→partner) and Y-score (partner→VPS54) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SNORA80E →	-1.233	-0.318	.006	.005	3	3
OV	ARHGEF26 →	-0.833	-0.361	.001	.001	3	2
OV	WASF2 →	-0.476	-0.285	.009	.001	2	3
OV	E2F2 →	-0.807	-0.312	.001	.005	3	2
LSCC	CPVL →	+0.411	+0.137	.004	.001	3	2
LSCC	QPCT →	+0.711	+0.138	.004	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,271 associations by consensus.

VPS54 vs SNORA80E — UCEC

Explore this scatter interactively →