VPS41

Across TCGA patient cohorts, VPS41 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,085 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible VPS41-associated proteins across cancer lineages are NUDCD3, PURB, and PHF11_S17. Each is linked with VPS41 in more than 8 cancer types. Because this analysis shows association rather than direction, both VPS41-to-partner and partner-to-VPS41 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VPS41 versus NUDCD3 in BRCA, with a Pearson correlation of 0.48.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (VPS41→partner) and Y-score (partner→VPS41) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	NUDCD3 →	+0.394	+0.615	<.001	<.001	3	9
OV	PURB →	+0.376	+0.481	.002	.001	3	7
HNSC	PHF11_S17 →	-0.534	-0.582	.001	.001	3	5
BRCA	RPL6 →	-0.450	-0.360	<.001	.002	3	5
LUAD	SDF2L1 →	-0.521	-0.548	<.001	<.001	3	5
BRCA	SPCS2 →	-0.538	-0.362	.003	.008	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,085 associations by consensus.

VPS41 vs NUDCD3 — BRCA

Explore this scatter interactively →