VPS37D

Across TCGA cell cohorts, VPS37D mutation is significantly associated with the mutation status of many other genes, with 386 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible VPS37D-associated genes across cancer lineages are ANKRD16, PIGK, and IGSF3. Each is linked with VPS37D in more than 1 cancer types. Because this analysis shows association rather than direction, both VPS37D-to-partner and partner-to-VPS37D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ANKRD16 grouped by VPS37D-low versus VPS37D-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VPS37D→partner) and Y-score (partner→VPS37D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ANKRD16 →	+4.329	+4.329	.001	.001	1	2
LARGE_INTESTINE	PIGK →	+3.329	+3.799	.005	.005	1	2
LARGE_INTESTINE	IGSF3 →	+2.159	+3.807	.007	.007	1	2
LARGE_INTESTINE	ZNF367 →	+4.329	+4.329	.001	.001	1	2
LARGE_INTESTINE	PGK2 →	+4.329	+4.329	.001	.001	1	2
LARGE_INTESTINE	TUBB6 →	+3.007	+3.584	.008	.008	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 386 associations by consensus.

ANKRD16 by VPS37D expression — LARGE_INTESTINE

Explore this box plot interactively →