VPS37C

Across TCGA patient cohorts, VPS37C mutation is significantly associated with the RNA expression of many other genes, with 1,672 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible VPS37C-associated genes across cancer lineages are RN7SL518P, IGHD7-27, and ATP5F1AP10. Each is linked with VPS37C in more than 1 cancer types. Because this analysis shows association rather than direction, both VPS37C-to-partner and partner-to-VPS37C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL518P grouped by VPS37C-low versus VPS37C-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VPS37C→partner) and Y-score (partner→VPS37C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RN7SL518P →	+0.399	+4.693	.007	.007	3	2
READ	IGHD7-27 →	+1.606	+5.039	<.001	.008	3	2
READ	ATP5F1AP10 →	+0.065	+5.653	<.001	.003	3	1
COAD	MIR374A →	+0.581	+5.392	<.001	.002	3	1
COAD	RNU6-633P →	+0.816	+5.374	<.001	.001	3	1
COAD	RNA5SP319 →	+0.514	+5.271	.004	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,672 associations by consensus.

RN7SL518P by VPS37C expression — COAD

Explore this box plot interactively →