VPS37A

Across TCGA patient cohorts, VPS37A RNA expression is significantly associated with the mutation status of many other genes, with 10,883 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible VPS37A-associated genes across cancer lineages are AHNAK2, FAT1, and ASTN1. Each is linked with VPS37A in more than 4 cancer types. Because this analysis shows association rather than direction, both VPS37A-to-partner and partner-to-VPS37A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AHNAK2 grouped by VPS37A-low versus VPS37A-high in COAD.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VPS37A→partner) and Y-score (partner→VPS37A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	AHNAK2 →	+3.013	+0.397	<.001	<.001	3	5
STAD	FAT1 →	+2.584	+0.313	.009	.007	3	5
LUAD	ASTN1 →	+1.985	+0.335	<.001	<.001	3	4
COAD	PCDH15 →	+1.778	+0.286	.007	.003	3	4
HNSC	ROS1 →	+2.427	+0.324	<.001	.006	3	4
SKCM	DNAH1 →	+1.972	+0.354	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,883 associations by consensus.

AHNAK2 by VPS37A expression — COAD

Explore this box plot interactively →