Across TCGA patient cohorts, VPS33B RNA expression is significantly associated with the protein abundance of many other proteins, with 11,104 significant associations in total. GBM shows the largest number of these associations.

The most reproducible VPS33B-associated proteins across cancer lineages are SIN3A, MORF4L1, and RNF20. Each is linked with VPS33B in more than 5 cancer types. Because this analysis shows association rather than direction, both VPS33B-to-partner and partner-to-VPS33B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (VPS33B→partner) and Y-score (partner→VPS33B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SIN3A →	+0.225	+0.274	<.001	<.001	3	6
LSCC	MORF4L1 →	+0.351	+0.462	<.001	<.001	3	6
LSCC	RNF20 →	+0.237	+0.387	.003	.002	3	5
LSCC	TIMELESS_S1121 →	+1.519	+0.544	<.001	<.001	3	5
GBM	CTDSPL2 →	+0.379	+0.284	<.001	<.001	3	5
GBM	EDC3 →	+0.364	+0.393	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,104 associations by consensus.

Exploration

VPS33B survival (RNA) · tumor vs normal (RNA) · all VPS33B data types