Across TCGA patient cohorts, VPS33B mutation is significantly associated with the RNA expression of many other genes, with 1,762 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible VPS33B-associated genes across cancer lineages are OR5T2, RN7SL728P, and ZNF519P4. Each is linked with VPS33B in more than 1 cancer types. Because this analysis shows association rather than direction, both VPS33B-to-partner and partner-to-VPS33B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VPS33B→partner) and Y-score (partner→VPS33B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	OR5T2 →	+0.070	+5.182	<.001	.007	3	2
BRCA	RN7SL728P →	+0.370	+5.317	.002	.006	3	2
BRCA	ZNF519P4 →	+0.337	+5.070	<.001	.008	3	2
BLCA	MIR519A1 →	+0.806	+4.685	<.001	.007	3	2
CESC	OR1A1 →	+0.054	+6.144	<.001	.001	3	2
UCEC	LINC01607 →	-0.542	-2.679	.002	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,762 associations by consensus.

Exploration

VPS33B survival (RNA) · tumor vs normal (RNA) · all VPS33B data types