Across TCGA patient cohorts, VPS33B-DT mutation is significantly associated with the RNA expression of many other genes, with 81 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible VPS33B-DT-associated genes across cancer lineages are UTRN, RN7SL601P, and RNU2-53P. Each is linked with VPS33B-DT in more than 1 cancer types. Because this analysis shows association rather than direction, both VPS33B-DT-to-partner and partner-to-VPS33B-DT results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VPS33B-DT→partner) and Y-score (partner→VPS33B-DT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	UTRN →	+0.806	+3.234	.005	.009	3	1
SKCM	RN7SL601P →	+0.249	+7.816	<.001	.008	3	1
SKCM	RNU2-53P →	+0.434	+7.816	<.001	.008	3	1
UCEC	ARL1 →	+0.634	+3.217	.002	.009	3	1
UCEC	EXOC5P1 →	+0.170	+3.287	<.001	.008	3	1
UCEC	RNU1-58P →	+0.626	+2.637	.003	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 81 associations by consensus.

Exploration

VPS33B-DT survival (RNA) · tumor vs normal (RNA) · all VPS33B-DT data types