VPS28

Across TCGA patient cohorts, VPS28 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,101 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible VPS28-associated proteins across cancer lineages are SCRIB, PYCR3, and AGO2. Each is linked with VPS28 in more than 6 cancer types. Because this analysis shows association rather than direction, both VPS28-to-partner and partner-to-VPS28 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VPS28 versus SCRIB in OV, with a Pearson correlation of 0.58.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (VPS28→partner) and Y-score (partner→VPS28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SCRIB →	+0.419	+0.637	<.001	<.001	3	7
OV	PYCR3 →	+0.400	+0.569	<.001	<.001	3	5
OV	AGO2 →	+0.290	+0.839	<.001	<.001	3	5
OV	CYC1 →	+0.711	+0.640	<.001	<.001	3	5
LSCC	FAM83H →	+0.576	+0.483	.007	<.001	3	5
PDAC	NDRG1_S319 →	+1.669	+0.549	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,101 associations by consensus.

VPS28 vs SCRIB — OV

Explore this scatter interactively →