VPS28

Across TCGA patient cohorts, VPS28 protein abundance is significantly associated with the RNA expression of many other genes, with 5,874 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible VPS28-associated genes across cancer lineages are BCL2L11, SOD2, and FLNB. Each is linked with VPS28 in more than 3 cancer types. Because this analysis shows association rather than direction, both VPS28-to-partner and partner-to-VPS28 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VPS28 versus BCL2L11 in UCEC, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VPS28→partner) and Y-score (partner→VPS28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	BCL2L11 →	-0.580	-0.183	.001	.003	3	4
HNSC	SOD2 →	-1.123	-0.221	<.001	<.001	3	3
PDAC	FLNB →	+0.667	+0.314	.002	<.001	3	3
HNSC	FAM171A1 →	-1.069	-0.182	<.001	.004	3	3
PDAC	S100A12 →	-0.888	-0.317	.001	<.001	3	3
HNSC	C18orf54 →	-0.688	-0.163	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,874 associations by consensus.

VPS28 vs BCL2L11 — UCEC

Explore this scatter interactively →