VPS28

Across TCGA patient cohorts, VPS28 protein abundance is significantly associated with the protein abundance of many other proteins, with 19,451 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible VPS28-associated proteins across cancer lineages are TSG101, VPS37B, and LDHA. Each is linked with VPS28 in more than 8 cancer types. Because this analysis shows association rather than direction, both VPS28-to-partner and partner-to-VPS28 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VPS28 versus TSG101 in HNSC, with a Pearson correlation of 0.73.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (VPS28→partner) and Y-score (partner→VPS28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	TSG101 →	+0.259	+0.264	<.001	<.001	3	9
UCEC	VPS37B →	+0.412	+0.273	<.001	<.001	3	8
HNSC	LDHA →	+0.438	+0.228	<.001	<.001	3	7
PDAC	RNH1 →	+0.313	+0.221	<.001	<.001	3	6
PDAC	STAM →	+0.310	+0.261	<.001	<.001	3	6
PDAC	CAPN1 →	+0.287	+0.193	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,451 associations by consensus.

VPS28 vs TSG101 — HNSC

Explore this scatter interactively →