VPS28

Across TCGA cell cohorts, VPS28 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,969 significant associations in total. BONE shows the largest number of these associations.

The most reproducible VPS28-associated GO terms across cancer lineages are Peptidyl-lysine trimethylation, Response to sodium arsenite, and Central nervous system morphogenesis. Each is linked with VPS28 in more than 7 cancer types. Because this analysis shows association rather than direction, both VPS28-to-partner and partner-to-VPS28 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peptidyl-lysine trimethylation grouped by VPS28-low versus VPS28-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VPS28→partner) and Y-score (partner→VPS28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Peptidyl-lysine trimethylation →	-0.084	-0.723	.004	.001	3	8
LIVER	Response to sodium arsenite →	+0.252	+0.719	<.001	.004	3	8
BLOOD_Leukemia	Central nervous system morphogenesis →	-0.428	-0.464	.003	.001	3	7
BONE	Cellular response to salt →	+0.155	+1.466	<.001	<.001	3	7
LIVER	Cellular response to sodium arsenite →	+0.234	+0.742	<.001	.003	3	7
UPPER_AERODIGESTIVE_TRACT	Lipid modification →	+0.037	+0.650	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,969 associations by consensus.

Peptidyl-lysine trimethylation by VPS28 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →