VPS28

Across TCGA cell cohorts, VPS28 protein abundance is significantly associated with the RNA expression of many other genes, with 1,573 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible VPS28-associated genes across cancer lineages are CLPP, IL2RG, and MS4A1. Each is linked with VPS28 in more than 2 cancer types. Because this analysis shows association rather than direction, both VPS28-to-partner and partner-to-VPS28 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VPS28 versus CLPP in BLOOD_Leukemia, with a Pearson correlation of -0.67.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VPS28→partner) and Y-score (partner→VPS28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	CLPP →	-0.509	-1.168	.004	.006	3	3
CNS	IL2RG →	-0.980	-2.240	.004	.005	3	2
CNS	MS4A1 →	-1.333	-2.649	<.001	<.001	3	2
CNS	STK19 →	+0.687	+1.919	<.001	.002	3	2
CNS	ATP6V1FNB →	-0.563	-1.930	.003	.002	3	2
BLOOD_Leukemia	MRPL34 →	-0.681	-1.168	.005	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,573 associations by consensus.

VPS28 vs CLPP — BLOOD_Leukemia

Explore this scatter interactively →