VPS26B

Across TCGA patient cohorts, VPS26B protein abundance is significantly associated with the RNA expression of many other genes, with 13,310 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible VPS26B-associated genes across cancer lineages are TMEM218, ACAD8, and THYN1. Each is linked with VPS26B in more than 6 cancer types. Because this analysis shows association rather than direction, both VPS26B-to-partner and partner-to-VPS26B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VPS26B versus TMEM218 in HNSC, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VPS26B→partner) and Y-score (partner→VPS26B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	TMEM218 →	+0.504	+0.236	.005	<.001	3	7
LUAD	ACAD8 →	+0.802	+0.213	<.001	<.001	3	7
OV	THYN1 →	+0.711	+0.300	<.001	.002	3	6
OV	SRPRA →	+0.463	+0.338	.003	.001	3	6
BRCA	SNX19 →	+0.476	+0.212	<.001	<.001	3	6
COAD	DACT3 →	+0.663	+0.175	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,310 associations by consensus.

VPS26B vs TMEM218 — HNSC

Explore this scatter interactively →