VPS25

Across TCGA patient cohorts, VPS25 protein abundance is significantly associated with the protein abundance of many other proteins, with 15,563 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible VPS25-associated proteins across cancer lineages are VPS36, SNF8, and ESD. Each is linked with VPS25 in more than 9 cancer types. Because this analysis shows association rather than direction, both VPS25-to-partner and partner-to-VPS25 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VPS25 versus VPS36 in OV, with a Pearson correlation of 0.47.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (VPS25→partner) and Y-score (partner→VPS25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	VPS36 →	+0.328	+0.368	<.001	<.001	3	10
BRCA	SNF8 →	+0.290	+0.304	<.001	<.001	3	10
CCRCC	ESD →	+0.387	+0.214	<.001	<.001	3	7
UCEC	COG2 →	+0.339	+0.281	<.001	<.001	3	7
UCEC	COG3 →	+0.399	+0.382	<.001	<.001	3	6
HNSC	NCAPG_S674 →	-1.028	-0.327	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,563 associations by consensus.

VPS25 vs VPS36 — OV

Explore this scatter interactively →