VPS25

Across TCGA cell cohorts, VPS25 protein abundance is significantly associated with the RNA expression of many other genes, with 3,204 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible VPS25-associated genes across cancer lineages are BABAM1, PPP1R14B, and SNAPC4. Each is linked with VPS25 in more than 3 cancer types. Because this analysis shows association rather than direction, both VPS25-to-partner and partner-to-VPS25 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VPS25 versus BABAM1 in LUNG_NSCLC_LUAD, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VPS25→partner) and Y-score (partner→VPS25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	BABAM1 →	+0.509	+0.669	.003	.002	3	4
LUNG_NSCLC_LUAD	PPP1R14B →	+0.571	+0.696	.004	.002	3	4
STOMACH	SNAPC4 →	-1.085	-0.958	.003	.001	3	4
KIDNEY	STMN3 →	+3.557	+1.589	<.001	.002	3	4
OESOPHAGUS	PANK3 →	-0.642	-0.755	.005	<.001	3	3
OESOPHAGUS	ELL3 →	-1.569	-0.843	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,204 associations by consensus.

VPS25 vs BABAM1 — LUNG_NSCLC_LUAD

Explore this scatter interactively →