VPS25

Across TCGA cell cohorts, VPS25 protein abundance is significantly associated with the protein abundance of many other proteins, with 2,769 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible VPS25-associated proteins across cancer lineages are PRKCD, PSMD8, and SNRPD2. Each is linked with VPS25 in more than 4 cancer types. Because this analysis shows association rather than direction, both VPS25-to-partner and partner-to-VPS25 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VPS25 versus PRKCD in BLOOD_Leukemia, with a Pearson correlation of 0.44.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (VPS25→partner) and Y-score (partner→VPS25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	PRKCD →	+1.404	+0.985	<.001	<.001	3	5
LUNG_SCLC	PSMD8 →	+0.668	+0.698	<.001	<.001	3	5
BLOOD_Leukemia	SNRPD2 →	-0.178	-0.564	.004	.001	3	4
BLOOD_Leukemia	COPB1 →	+0.394	+0.830	<.001	<.001	3	4
UPPER_AERODIGESTIVE_TRACT	ECPAS →	+0.934	+1.786	.002	<.001	3	4
LUNG_SCLC	PSMD6 →	+0.573	+0.742	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,769 associations by consensus.

VPS25 vs PRKCD — BLOOD_Leukemia

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