VPS18

Across TCGA patient cohorts, VPS18 protein abundance is significantly associated with the RNA expression of many other genes, with 15,421 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible VPS18-associated genes across cancer lineages are PARVG, TLR7, and PLK1. Each is linked with VPS18 in more than 6 cancer types. Because this analysis shows association rather than direction, both VPS18-to-partner and partner-to-VPS18 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VPS18 versus PARVG in GBM, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VPS18→partner) and Y-score (partner→VPS18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PARVG →	+0.719	+0.142	.002	.005	3	7
GBM	TLR7 →	+1.108	+0.216	<.001	<.001	3	7
BRCA	PLK1 →	-0.878	-0.177	<.001	<.001	3	7
GBM	PBK →	-1.432	-0.196	<.001	<.001	3	7
HNSC	GPR65 →	+0.615	+0.171	.004	<.001	3	6
COAD	OLR1 →	+1.111	+0.142	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,421 associations by consensus.

VPS18 vs PARVG — GBM

Explore this scatter interactively →