VPS13B

Across TCGA patient cohorts, VPS13B RNA expression is significantly associated with the protein abundance of many other proteins, with 14,491 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible VPS13B-associated proteins across cancer lineages are PUF60, RBM12B, and KHSRP. Each is linked with VPS13B in more than 5 cancer types. Because this analysis shows association rather than direction, both VPS13B-to-partner and partner-to-VPS13B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VPS13B versus PUF60 in LSCC, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (VPS13B→partner) and Y-score (partner→VPS13B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PUF60 →	+0.163	+0.329	<.001	<.001	3	5
GBM	RBM12B →	+0.259	+0.306	<.001	<.001	3	5
LSCC	KHSRP →	+0.286	+0.409	<.001	<.001	3	5
LUAD	STK3 →	+0.377	+0.454	<.001	<.001	2	6
GBM	TRIM24 →	+0.445	+0.309	<.001	<.001	3	4
BRCA	THUMPD1 →	+0.423	+0.777	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,491 associations by consensus.

VPS13B vs PUF60 — LSCC

Explore this scatter interactively →