VPREB3

Across TCGA cell cohorts, VPREB3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,654 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible VPREB3-associated GO terms across cancer lineages are Mitochondrial respiratory chain complex assembly, Fibrinolysis, and Positive regulation of striated muscle contraction. Each is linked with VPREB3 in more than 9 cancer types. Because this analysis shows association rather than direction, both VPREB3-to-partner and partner-to-VPREB3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial respiratory chain complex assembly grouped by VPREB3-low versus VPREB3-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VPREB3→partner) and Y-score (partner→VPREB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Mitochondrial respiratory chain complex assembly →	+0.090	+0.782	<.001	.002	3	10
LARGE_INTESTINE	Fibrinolysis →	-1.090	-0.582	.002	<.001	3	8
OVARY	Positive regulation of striated muscle contraction →	-0.173	-0.412	.003	.005	3	8
SOFT_TISSUE	Regulation of coagulation →	-0.127	-0.445	.005	.001	3	7
KIDNEY	B cell receptor signaling pathway →	-0.149	-0.602	.003	.002	3	7
LARGE_INTESTINE	Sulfur amino acid catabolic process →	+0.122	+0.510	<.001	.002	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,654 associations by consensus.

Mitochondrial respiratory chain complex assembly by VPREB3 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →