VPREB1

Across TCGA patient cohorts, VPREB1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,887 significant associations in total. STAD shows the largest number of these associations.

The most reproducible VPREB1-associated GO terms across cancer lineages are Antigen receptor-mediated signaling pathway, Immunological synapse formation, and Positive T cell selection. Each is linked with VPREB1 in more than 17 cancer types. Because this analysis shows association rather than direction, both VPREB1-to-partner and partner-to-VPREB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Antigen receptor-mediated signaling pathway grouped by VPREB1-low versus VPREB1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VPREB1→partner) and Y-score (partner→VPREB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Antigen receptor-mediated signaling pathway →	+0.071	+0.151	<.001	<.001	3	17
PAAD	Immunological synapse formation →	+0.115	+0.088	<.001	<.001	3	17
PAAD	Positive T cell selection →	+0.071	+0.085	<.001	<.001	3	17
STAD	T cell receptor signaling pathway →	+0.066	+0.149	<.001	<.001	3	16
PAAD	B cell receptor signaling pathway →	+0.099	+0.099	<.001	<.001	3	16
STAD	Immunoglobulin production →	+0.074	+0.135	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,887 associations by consensus.

Antigen receptor-mediated signaling pathway by VPREB1 expression — STAD

Explore this box plot interactively →