VPREB1

Across TCGA pan-cancer cohorts, VPREB1 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of VPREB1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where VPREB1 RNA is repressed in tumor relative to normal tissue. In most cancer types VPREB1 is over-expressed in tumor, although a few such as COAD show the opposite, repressed pattern.

COAD, ESCA, and LUAD are the cancer types where VPREB1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in VPREB1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	IV	−0.168	.033	2	view →
ESCA	All	II,III,IV	+0.075	.037	2	view →
LUAD	All	All	+0.049	.014	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

VPREB1–COAD

Open the COAD breakdown →