VPREB1

Across TCGA patient cohorts, VPREB1 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible VPREB1-associated genes across cancer lineages are Adipocytes, MPP, and CD4+ Tcm. Each is linked with VPREB1 in more than 1 cancer types. Because this analysis shows association rather than direction, both VPREB1-to-partner and partner-to-VPREB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Adipocytes grouped by VPREB1-low versus VPREB1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VPREB1→partner) and Y-score (partner→VPREB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Adipocytes →	+0.024	+1.915	.036	.046	3	1
SKCM	MPP →	+0.029	+2.510	<.001	.011	3	1
COAD	CD4+ Tcm →	+0.017	+6.156	<.001	.018	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Adipocytes by VPREB1 expression — SKCM

Explore this box plot interactively →