VPREB1

Across TCGA cell cohorts, VPREB1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,386 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible VPREB1-associated GO terms across cancer lineages are Regulation of hippo signaling, Negative regulation of calcium ion transport into cytosol, and Neutrophil-mediated killing of fungus. Each is linked with VPREB1 in more than 7 cancer types. Because this analysis shows association rather than direction, both VPREB1-to-partner and partner-to-VPREB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of hippo signaling grouped by VPREB1-low versus VPREB1-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VPREB1→partner) and Y-score (partner→VPREB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Regulation of hippo signaling →	+0.067	+0.050	.008	.007	3	7
URINARY_TRACT	Negative regulation of calcium ion transport into cytosol →	-0.180	-0.198	<.001	<.001	3	7
URINARY_TRACT	Neutrophil-mediated killing of fungus →	+0.221	+0.197	<.001	<.001	3	7
PANCREAS	Positive regulation of anaphase-promoting complex-dependent catabolic process →	+0.083	+0.080	.003	.002	1	8
PANCREAS	Regulation of peptidyl-lysine acetylation →	+0.086	+0.106	.006	.003	3	6
LARGE_INTESTINE	Cell division →	+0.037	+0.121	.001	.006	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,386 associations by consensus.

Regulation of hippo signaling by VPREB1 expression — LIVER

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