VPREB1

Across TCGA cell cohorts, VPREB1 protein abundance is significantly associated with the RNA expression of many other genes, with 70 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible VPREB1-associated genes across cancer lineages are IGDCC4, CEP126, and RBPJL. Each is linked with VPREB1 in more than 1 cancer types. Because this analysis shows association rather than direction, both VPREB1-to-partner and partner-to-VPREB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VPREB1 versus IGDCC4 in BLOOD_Leukemia, with a Pearson correlation of -0.66.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VPREB1→partner) and Y-score (partner→VPREB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	IGDCC4 →	-0.118	-2.248	.005	.003	3	1
BLOOD_Leukemia	CEP126 →	-1.696	-3.144	<.001	.009	3	1
BLOOD_Leukemia	RBPJL →	-0.250	-2.915	.003	.003	3	1
BLOOD_Leukemia	KRT17 →	-0.728	-2.120	.001	.006	3	1
BLOOD_Leukemia	DDC →	-0.580	-3.167	<.001	.009	3	1
BLOOD_Leukemia	CGA →	-0.108	-2.120	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 70 associations by consensus.

VPREB1 vs IGDCC4 — BLOOD_Leukemia

Explore this scatter interactively →