VPREB1

Across TCGA cell cohorts, VPREB1 protein abundance is significantly associated with the drug of many other genes, with 16 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible VPREB1-associated genes across cancer lineages are Rapamycin, FS106, and N22899-6-C1. Each is linked with VPREB1 in more than 1 cancer types. Because this analysis shows association rather than direction, both VPREB1-to-partner and partner-to-VPREB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Rapamycin grouped by VPREB1-low versus VPREB1-high in BLOOD_Leukemia.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VPREB1→partner) and Y-score (partner→VPREB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Rapamycin →	-0.409	-1.042	.028	.029	3	1
BLOOD_Leukemia	FS106 →	-0.902	-1.167	.002	.023	3	1
BLOOD_Leukemia	N22899-6-C1 →	-0.486	-3.044	<.001	.020	3	1
BLOOD_Leukemia	BPTES →	-0.393	-1.901	.007	.029	3	1
BLOOD_Leukemia	PLK_6522 →	-1.120	-3.290	.013	.032	3	1
BLOOD_Leukemia	T0901317 →	+0.420	+1.107	.035	.031	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

Rapamycin by VPREB1 expression — BLOOD_Leukemia

Explore this box plot interactively →