VNN3

Across TCGA patient cohorts, VNN3 protein abundance is significantly associated with the RNA expression of many other genes, with 2,849 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible VNN3-associated genes across cancer lineages are EXO1, CDKN3, and CENPI. Each is linked with VNN3 in more than 3 cancer types. Because this analysis shows association rather than direction, both VNN3-to-partner and partner-to-VNN3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VNN3 versus EXO1 in HNSC, with a Pearson correlation of 0.68.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VNN3→partner) and Y-score (partner→VNN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	EXO1 →	+1.383	+1.120	.002	.005	3	4
BRCA	CDKN3 →	+1.859	+1.134	<.001	.005	3	3
BRCA	CENPI →	+1.431	+1.431	.003	.008	3	3
BRCA	FOXM1 →	+2.118	+1.727	.009	.009	3	3
LSCC	MSH6 →	+0.633	+0.608	<.001	.005	3	3
BRCA	CDC20 →	+2.689	+1.085	<.001	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,849 associations by consensus.

VNN3 vs EXO1 — HNSC

Explore this scatter interactively →