VNN3

Across TCGA cell cohorts, VNN3 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,031 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible VNN3-associated GO terms across cancer lineages are Vertebrate eye-specific patterning, Defense response to bacterium, and Opsonization. Each is linked with VNN3 in more than 7 cancer types. Because this analysis shows association rather than direction, both VNN3-to-partner and partner-to-VNN3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vertebrate eye-specific patterning grouped by VNN3-low versus VNN3-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VNN3→partner) and Y-score (partner→VNN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Vertebrate eye-specific patterning →	+0.795	+0.021	.003	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Defense response to bacterium →	+0.100	+1.062	<.001	.002	3	8
CNS	Opsonization →	+1.039	+0.019	<.001	.004	3	8
LARGE_INTESTINE	Complement-mediated synapse pruning →	+0.849	+0.018	.003	.001	3	8
OVARY	Complement activation, lectin pathway →	+1.253	+0.270	<.001	.006	3	7
CNS	Basement membrane disassembly →	+0.792	+0.026	.003	.006	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,031 associations by consensus.

Vertebrate eye-specific patterning by VNN3 expression — LARGE_INTESTINE

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