VNN2

Across TCGA patient cohorts, VNN2 mutation is significantly associated with the RNA expression of many other genes, with 2,153 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible VNN2-associated genes across cancer lineages are LINC01202, UHRF1, and PHF5A. Each is linked with VNN2 in more than 1 cancer types. Because this analysis shows association rather than direction, both VNN2-to-partner and partner-to-VNN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01202 grouped by VNN2-low versus VNN2-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VNN2→partner) and Y-score (partner→VNN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	LINC01202 →	+0.926	+4.231	<.001	.003	3	2
UCEC	UHRF1 →	+1.024	+2.534	<.001	<.001	3	2
UCEC	PHF5A →	+0.452	+2.137	<.001	.001	3	2
UCEC	E2F1 →	+0.725	+1.818	.001	.002	3	2
UCEC	OIP5 →	+0.710	+3.103	<.001	<.001	3	2
UCEC	TRIM35 →	+0.466	+2.332	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,153 associations by consensus.

LINC01202 by VNN2 expression — BRCA

Explore this box plot interactively →