Across TCGA pan-cancer cohorts, VN1R42P RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of VN1R42P’s most consistent transcriptional readouts.
The strongest signal is observed in lung adenocarcinoma (LUAD), where VN1R42P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types VN1R42P is over-expressed in tumor, although a few such as THCA and LUSC show the opposite, repressed pattern.
LUAD, BLCA, and BRCA are the cancer types where VN1R42P tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in VN1R42P RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.