Q-omics provides the consensus-scored VN1R42P profile across patient tissues and cancer cell-line models. VN1R42P expression is associated with patient survival in 23 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, VN1R42P is differentially expressed in 14, with the highest sampling consensus in LUAD. Additionally, VN1R42P RNA expression shows 19,145 significant gene co-expression associations, with the highest sampling consensus in UVM. Together, these results highlight KIRC, LUAD, and UVM as cancer lineages where VN1R42P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for VN1R42P — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes VN1R42P survival associations across molecular data types. VN1R42P RNA expression shows survival associations in the most cancer types (23). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible VN1R42P RNA expression–survival associations across cancer types. High VN1R42P expression shows unfavorable associations in KIRC, LIHC and CESC, but favorable associations in SKCM, LAML and READ. The KIRC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for VN1R42P RNA expression.
This table summarizes VN1R42P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 14. The strongest signals are observed in BRCA for RNA.
This table ranks reproducible tumor–normal expression differences for VN1R42P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. VN1R42P shows lower tumor expression in THCA and higher tumor expression in LUAD, BLCA, BRCA, STAD and LUSC. The LUAD box plot shows higher VN1R42P RNA expression in tumor versus normal tissue (log2 FC = +0.572, t-test p < 0.001).
This table shows molecular features associated with VN1R42P in patient tissues and cancer cell lines. In patient samples, VN1R42P shows the broadest associations at the RNA and protein expression levels, with UVM recurring as the lineage with the largest associated feature set.
