Across TCGA cell cohorts, VN1R4 mutation is significantly associated with the RNA expression of many other genes, with 21 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible VN1R4-associated genes across cancer lineages are SLC15A5, CBLIF, and ARHGAP36. Each is linked with VN1R4 in more than 1 cancer types. Because this analysis shows association rather than direction, both VN1R4-to-partner and partner-to-VN1R4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VN1R4→partner) and Y-score (partner→VN1R4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	SLC15A5 →	+0.029	+5.643	<.001	.002	3	1
BLOOD_Leukemia	CBLIF →	+0.109	+3.769	<.001	.008	3	1
BLOOD_Leukemia	ARHGAP36 →	+0.016	+3.944	<.001	.006	3	1
BLOOD_Leukemia	C11orf53 →	+0.029	+3.551	<.001	.009	3	1
BLOOD_Leukemia	IL3 →	+0.058	+4.786	<.001	<.001	3	1
BLOOD_Leukemia	MAGEB10 →	+0.183	+3.874	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

Exploration

VN1R4 survival (RNA) · tumor vs normal (RNA) · all VN1R4 data types