VN1R3

Across TCGA cell cohorts, VN1R3 RNA expression is significantly associated with the mutation status of many other genes, with 63 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible VN1R3-associated genes across cancer lineages are HNF4G, STEAP1B, and STIM2. Each is linked with VN1R3 in more than 1 cancer types. Because this analysis shows association rather than direction, both VN1R3-to-partner and partner-to-VN1R3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HNF4G grouped by VN1R3-low versus VN1R3-high in LUNG_NSCLC_LUAD.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VN1R3→partner) and Y-score (partner→VN1R3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	HNF4G →	+3.944	+0.010	.006	<.001	3	2
BONE	STEAP1B →	+4.169	+0.035	.008	<.001	3	1
BONE	STIM2 →	+5.169	+0.046	.004	<.001	3	1
BONE	DPAGT1 →	+4.169	+0.035	.008	<.001	3	1
BONE	ROBO2 →	+4.169	+0.035	.008	<.001	3	1
LUNG_NSCLC_LUSC	MMS22L →	+3.584	+0.020	.003	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 63 associations by consensus.

HNF4G by VN1R3 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →