VN1R3

Across TCGA pan-cancer cohorts, VN1R3 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated VN1R3 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher VN1R3 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated VN1R3 expression acts as an unfavorable survival marker, although some lineages such as SARC and PAAD show a favorable association.

KIRC, UCEC, and THCA are the cancer types where VN1R3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	II,III,IV	0.617	0.803	.002	105	view →
UCEC	OS	Tertile	All	0.396	0.704	<.001	96	view →
THCA	DFS	Tertile	IV	0.391	0.900	<.001	63	view →
OV	DFS	Tertile	II,III,IV	0.289	0.397	.002	54	view →
BLCA	DFS	Tertile	All	0.445	0.633	.035	45	view →
COAD	OS	Tertile	III,IV	0.157	0.791	.001	30	view →
ACC	DFS	Tertile	All	0.195	0.748	.003	18	view →
SKCM	DFS	Tertile	II,III,IV	0.252	0.596	.022	15	view →
SARC	OS	Tertile	All	1.000	0.804	.021	12	view →
PAAD	DFS	Tertile	All	1.000	0.332	.027	12	view →
PRAD	OS	Tertile	All	0.946	0.996	.046	6	view →
THYM	DFS	Tertile	II,III,IV	0.856	0.927	.048	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

VN1R3–KIRC (OS)

Open the KIRC breakdown →