Across TCGA patient cohorts, VN1R2 mutation is significantly associated with the RNA expression of many other genes, with 2,812 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible VN1R2-associated genes across cancer lineages are PXMP2, ELAC2, and HAUS1P2. Each is linked with VN1R2 in more than 3 cancer types. Because this analysis shows association rather than direction, both VN1R2-to-partner and partner-to-VN1R2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VN1R2→partner) and Y-score (partner→VN1R2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PXMP2 →	+0.768	+2.923	<.001	<.001	3	4
UCEC	ELAC2 →	+0.439	+3.740	<.001	<.001	3	3
UCEC	HAUS1P2 →	+0.161	+2.216	<.001	.001	3	3
LUSC	MIR6786 →	+0.275	+4.578	<.001	.005	3	3
UCEC	CDKN3 →	+0.801	+2.673	<.001	<.001	3	3
UCEC	PSMB6 →	+0.473	+3.459	<.001	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,812 associations by consensus.

Exploration

VN1R2 survival (RNA) · tumor vs normal (RNA) · all VN1R2 data types