Across TCGA cell cohorts, VN1R2 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible VN1R2-associated genes across cancer lineages are FABP9, CTRB1, and ZPBP2. Each is linked with VN1R2 in more than 1 cancer types. Because this analysis shows association rather than direction, both VN1R2-to-partner and partner-to-VN1R2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VN1R2→partner) and Y-score (partner→VN1R2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	FABP9 →	+0.060	+5.357	<.001	.003	3	1
SKIN	CTRB1 →	+0.143	+3.404	.006	.006	3	1
SKIN	ZPBP2 →	+0.015	+3.217	<.001	.006	3	1
SKIN	CLEC2A →	+0.048	+3.217	<.001	.006	3	1
SKIN	LBHD2 →	+0.147	+2.925	<.001	.007	3	1
LARGE_INTESTINE	OR5P3 →	+0.145	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration

VN1R2 survival (RNA) · tumor vs normal (RNA) · all VN1R2 data types