VMP1

Across TCGA pan-cancer cohorts, VMP1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated VMP1 data layer compared with 31 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher VMP1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated VMP1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and HNSC show a favorable association.

CCRCC, PDAC, and UCEC are the cancer types where VMP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Quartile	All	0.705	1.000	<.001	51	view →
PDAC	DFS	Quartile	All	0.302	0.642	.009	18	view →
UCEC	OS	Median	II,III,IV	1.000	0.620	.011	14	view →
HNSC	OS	Median	II,III,IV	0.896	0.811	.023	11	view →
LSCC	DFS	Tertile	All	0.669	0.894	.009	4	view →
LUAD	DFS	Median	All	0.973	0.824	.028	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

VMP1–CCRCC (OS)

Open the CCRCC breakdown →