VMP1

Across TCGA pan-cancer cohorts, VMP1 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of VMP1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where VMP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types VMP1 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

HNSC, KIRC, and KICH are the cancer types where VMP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in VMP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	III,IV	+0.901	<.001	12	view →
KIRC	Male	All	+0.695	<.001	11	view →
KICH	Female	II,III,IV	−2.575	<.001	9	view →
LUAD	Male	II,III,IV	+1.256	<.001	9	view →
KIRP	All	All	+0.816	<.001	9	view →
LIHC	Male	III,IV	+1.085	<.001	8	view →
STAD	All	II,III,IV	+0.935	<.001	8	view →
BRCA	All	II,III,IV	+0.749	<.001	6	view →
COAD	Male	All	+0.638	.001	4	view →
LUSC	Male	All	+0.557	<.001	4	view →
CHOL	All	All	+2.201	<.001	3	view →
ESCA	All	All	+1.606	<.001	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

VMP1–HNSC

Open the HNSC breakdown →