VMP1

Across TCGA patient cohorts, VMP1 mutation is significantly associated with the RNA expression of many other genes, with 2,073 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible VMP1-associated genes across cancer lineages are CEP76, BAG1, and DAP. Each is linked with VMP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both VMP1-to-partner and partner-to-VMP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CEP76 grouped by VMP1-low versus VMP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VMP1→partner) and Y-score (partner→VMP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CEP76 →	+0.377	+2.148	.002	<.001	3	2
UCEC	BAG1 →	+0.452	+1.917	<.001	.008	3	2
UCEC	DAP →	+0.512	+3.032	<.001	<.001	3	2
UCEC	EIF2B2 →	+0.437	+3.742	<.001	<.001	3	2
UCEC	FAM98A →	+0.338	+2.609	.002	<.001	3	2
UCEC	ACO1 →	+0.475	+2.137	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,073 associations by consensus.

CEP76 by VMP1 expression — UCEC

Explore this box plot interactively →