VMP1

Across TCGA cell cohorts, VMP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,059 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible VMP1-associated GO terms across cancer lineages are Regulation of ATPase-coupled calcium transmembrane transporter activity, Interleukin-10-mediated signaling pathway, and Autophagosome membrane docking. Each is linked with VMP1 in more than 13 cancer types. Because this analysis shows association rather than direction, both VMP1-to-partner and partner-to-VMP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of ATPase-coupled calcium transmembrane transporter activity grouped by VMP1-low versus VMP1-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VMP1→partner) and Y-score (partner→VMP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Regulation of ATPase-coupled calcium transmembrane transporter activity →	+0.273	+0.964	<.001	<.001	3	14
BONE	Interleukin-10-mediated signaling pathway →	+0.258	+1.163	<.001	<.001	3	13
BREAST	Autophagosome membrane docking →	+0.100	+1.034	<.001	<.001	3	11
BONE	Oncostatin-M-mediated signaling pathway →	+0.206	+0.853	<.001	<.001	3	11
PANCREAS	Canonical NF-kappaB signal transduction →	+0.090	+0.740	<.001	.003	3	10
SOFT_TISSUE	Death-inducing signaling complex assembly →	+0.315	+1.234	.004	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,059 associations by consensus.

Regulation of ATPase-coupled calcium transmembrane transporter activity by VMP1 expression — LUNG_SCLC

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