Across TCGA cell cohorts, VIT mutation is significantly associated with the RNA expression of many other genes, with 25 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible VIT-associated genes across cancer lineages are USP17L20, BOD1L2, and RETN. Each is linked with VIT in more than 1 cancer types. Because this analysis shows association rather than direction, both VIT-to-partner and partner-to-VIT results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VIT→partner) and Y-score (partner→VIT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	USP17L20 →	+0.004	+3.604	<.001	.004	3	2
OESOPHAGUS	BOD1L2 →	+0.006	+4.906	<.001	.006	3	1
LUNG_SCLC	RETN →	+0.144	+4.523	<.001	.003	3	1
LUNG_SCLC	GSTT4 →	+0.013	+4.269	<.001	.005	3	1
STOMACH	KHDC3L →	+0.016	+3.662	<.001	.001	3	1
CNS	CCL16 →	+0.013	+3.772	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

Exploration

VIT survival (RNA) · tumor vs normal (RNA) · all VIT data types