VIRMA

Across TCGA patient cohorts, VIRMA RNA expression is significantly associated with the protein abundance of many other proteins, with 14,568 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible VIRMA-associated proteins across cancer lineages are RBM12B, YWHAZ, and BOP1. Each is linked with VIRMA in more than 7 cancer types. Because this analysis shows association rather than direction, both VIRMA-to-partner and partner-to-VIRMA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VIRMA versus RBM12B in GBM, with a Pearson correlation of 0.53.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (VIRMA→partner) and Y-score (partner→VIRMA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RBM12B →	+0.255	+0.253	<.001	<.001	3	8
OV	YWHAZ →	+0.437	+0.436	<.001	.002	3	7
LSCC	BOP1 →	+0.369	+0.459	<.001	<.001	3	7
OV	NBN →	+0.285	+0.397	<.001	<.001	3	6
LSCC	NOL6 →	+0.316	+0.363	<.001	<.001	3	6
LUAD	NUDCD1 →	+0.301	+0.449	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,568 associations by consensus.

VIRMA vs RBM12B — GBM

Explore this scatter interactively →